HIGHLIGHTED TOPIC The Physiology and Pathophysiology of the Hyperbaric and Diving Environments DNA damage after long-term repetitive hyperbaric oxygen exposure
نویسندگان
چکیده
Michael Gröger, Sükrü Öter, Vladislava Simkova, Markus Bolten, Andreas Koch, Volker Warninghoff, Michael Georgieff, Claus-Martin Muth, Günter Speit, and Peter Radermacher Sektion Anästhesiologische Pathopyhsiologie und Verfahrensentwicklung and Abteilung Humangenetik, Universitätsklinikum, Ulm; Schifffahrtmedizinisches Institut der Marine, Kronshagen, Germany; Fizyoloji Anabilim Dali, Gülhane Askeri Tip Akademisi, Ankara, Turkey; and Anesteziologicko-resuscitacni klinika, Fakultni nemocnice u sv Anny, Brnó, Czech Republic
منابع مشابه
DNA damage after long-term repetitive hyperbaric oxygen exposure.
A single exposure to hyperbaric oxygen (HBO), i.e., pure oxygen breathing at supra-atmospheric pressures, causes oxidative DNA damage in humans in vivo as well as in isolated lymphocytes of human volunteers. These DNA lesions, however, are rapidly repaired, and an adaptive protection is triggered against further oxidative stress caused by HBO exposure. Therefore, we tested the hypothesis that l...
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Tatyana N. Milovanova, Veena M. Bhopale, Elena M. Sorokina, Jonni S. Moore, Thomas K. Hunt, Martin Hauer-Jensen, Omaida C. Velazquez, and Stephen R. Thom Institute for Environmental Medicine, Departments of Pathology and Laboratory Medicine and Emergency Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania; Department of Surgery, University of California at San Franci...
متن کاملHIGHLIGHTED TOPIC The Physiology and Pathophysiology of the Hyperbaric and Diving Environments Arterial and pulmonary arterial hemodynamics and oxygen delivery/extraction in normal humans exposed to hyperbaric air and oxygen
Weaver LK, Howe S, Snow GL, Deru K. Arterial and pulmonary arterial hemodynamics and oxygen delivery/extraction in normal humans exposed to hyperbaric air and oxygen. J Appl Physiol 107: 336–345, 2009. First published April 30, 2009; doi:10.1152/japplphysiol.91012.2008.— Divers and hyperbaric chamber attendants breathe hyperbaric air routinely. Hyperbaric oxygen (HBO2) is used therapeutically f...
متن کاملThe physiology and pathophysiology of the hyperbaric and diving environments.
HUMAN EXPOSURE to the challenges of the underwater world has been traced back thousands of years (e.g., the diving women of Japan). However, the last century has seen an acceleration of activities with disparate foci on the “Silent World.” The variety and beauty of marine life attract growing numbers of recreational divers, and the pressing need for exploitation of new energy sources has led to...
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In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...
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